Ma J (1993) Block by ruthenium red of the ryanodine-activated calcium release channel of skeletal muscle. J Gen Physiol 102: 1031-1056

Maccarrone M (2003) The blissful state of endothelium. Thromb Haemost 89: 771-772

Maccarrone M (2004) Inhibition of anandamide hydrolysis: cells also know how to do it. Trends Mol Med 10: 13-14

Maccarrone M, Attina M, Bari M, Cartoni A, Ledent C, Finazzi-Agro A (2001) Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages. J Neurochem 78: 339-348

Maccarrone M, Attina M, Cartoni A, Bari M, Finazzi-Agro A (2001) Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. J Neurochem 76: 594-601

Maccarrone M, Bari M, Agro AF (1999) A sensitive and specific radiochromatographic assay of fatty acid amide hydrolase activity. Anal Biochem 267: 314-318

Maccarrone M, Bari M, Battista N, Di Rienzo M, Finazzi-Agro A (2001) Endogenous cannabinoids in neuronal and immune cells: Toxic effects, levels and degradation. Functional Neurology 16: 53-60

Maccarrone M, Bari M, Battista N, Finazzi-Agro A (2002) Endocannabinoid degradation, endotoxic shock and inflammation. Curr Drug Targets Inflamm Allergy 1: 53-63

Maccarrone M, Bari M, Battista N, Finazzi-Agro A (2002) Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and platelet activation. Blood 100: 4040-4048

Maccarrone M, Bari M, Di Rienzo M, Finazzi-Agro A, Rossi A (2003) Progesterone activates fatty acid amide hydrolase (FAAH) promoter in human T lymphocytes through the transcription factor Ikaros. Journal of Biological Chemistry 278: 32726-32732

Maccarrone M, Bari M, Di Rienzo M, Finazzi-Agro A, Rossi A (2003) Progesterone activates fatty acid amide hydrolase (FAAH) promoter in human T lymphocytes through the transcription factor Ikaros. Evidence for a synergistic effect of leptin. J Biol Chem 278: 32726-32732

Maccarrone M, Bari M, Finazzi-Agro A (2002) Quantification of anandamide content in animal cells and tissues: the normalization makes the difference. Lipids Health Dis 1: 4

Maccarrone M, Bari M, Lorenzon T, Bisogno T, Di Marzo V, Finazzi-Agro A (2000) Anandamide uptake by human endothelial cells and its regulation by nitric oxide. J Biol Chem 275: 13484-13492

Maccarrone M, Bari M, Menichelli A, Del Principe D, Agro AF (1999) Anandamide activates human platelets through a pathway independent of the arachidonate cascade. FEBS Lett 447: 277-282

MacCarrone M, Bari M, Menichelli A, Giuliani E, Del Principe D, Finazzi-Agro A (2001) Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. Eur J Biochem 268: 819-825

Maccarrone M, Bari M, Principe DD, Finazzi-Agro A (2003) Activation of human platelets by 2-arachidonoylglycerol is enhanced by serotonin. Thromb Haemost 89: 340-347

Maccarrone M, Bisogno T, Valensise H, Lazzarin N, Fezza F, Manna C, Di Marzo V, Finazzi-Agro A (2002) Low fatty acid amide hydrolase and high anandamide levels are associated with failure to achieve an ongoing pregnancy after IVF and embryo transfer. Mol Hum Reprod 8: 188-195

Maccarrone M, Cartoni A, Parolaro D, Margonelli A, Massi P, Bari M, Battista N, Finazzi-Agro A (2002) Cannabimimetic activity, binding, and degradation of stearoylethanolamide within the mouse central nervous system. Mol Cell Neurosci 21: 126-140

Maccarrone M, Cecconi S, Rossi G, Battista N, Pauselli R, Finazzi-Agro A (2003) Anandamide activity and degradation are regulated by early postnatal aging and follicle-stimulating hormone in mouse Sertoli cells. Endocrinology 144: 20-28

MacCarrone M, De Felici M, Bari M, Klinger F, Siracusa G, Finazzi-Agro A (2000) Down-regulation of anandamide hydrolase in mouse uterus by sex hormones. Eur J Biochem 267: 2991-2997

Maccarrone M, De Petrocellis L, Bari M, Fezza F, Salvati S, Di Marzo V, Finazzi-Agro A (2001) Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. Arch Biochem Biophys 393: 321-328

Maccarrone M, DeFelici M, Klinger FG, Battista N, Fezza F, Dainese E, Siracusa G, Finazzi-Agro A (2004) Mouse blastocysts release a lipid which activates anandamide hydrolase in intact uterus. Mol Hum Reprod 10: 215-221

Maccarrone M, Del Principe D, Finazzi-Agro A (2002) Endocannabinoids: new physiological (co-)agonists of human platelets. Thromb Haemost 88: 165-166

Maccarrone M, Di Rienzo M, Battista N, Gasperi V, Guerrieri P, Rossi A, Finazzi-Agro A (2003) The endocannabinoid system in human keratinocytes - Evidence that anandamide inhibits epidermal differentiation through CB1 receptordependent inhibition of protein kinase C, activating protein-1, and transglutaminase. Journal of Biological Chemistry 278: 33896-33903

Maccarrone M, di Rienzo M, Battista N, Gasperi V, Guerrieri P, Rossi A, Finazzi-Agro A (2003) The endocannabinoid system in human keratinocytes. Evidence that anandamide inhibits epidermal differentiation through CB1 receptor-dependent inhibition of protein kinase C, activating protein-1, and transglutaminase. Journal of Biological Chemistry 278: 33896-33903

Maccarrone M, Di Rienzo M, Battista N, Gasperi V, Guerrieri P, Rossi A, Finazzi-Agro A (2003) The endocannabinoid system in human keratinocytes. Evidence that anandamide inhibits epidermal differentiation through CB1 receptor-dependent inhibition of protein kinase C, activation protein-1, and transglutaminase. J Biol Chem 278: 33896-33903

Maccarrone M, Di Rienzo M, Finazzi-Agro A, Rossi A (2003) Leptin activates the anandamide hydrolase promoter in human T lymphocytes through STAT3. J Biol Chem 278: 13318-13324

Maccarrone M, Falciglia K, Di Rienzo M, Finazzi-Agro A (2002) Endocannabinoids, hormone-cytokine networks and human fertility. Prostaglandins Leukot Essent Fatty Acids 66: 309-317

Maccarrone M, Finazzi-Agro A (2000) Platelet activation: a new vascular activity of anandamide. FEBS Lett 483: 84-85

Maccarrone M, Finazzi-Agro A (2002) Endocannabinoids and their actions. Vitam Horm 65: 225-255

Maccarrone M, Finazzi-Agro A (2003) The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis. Cell Death Differ 10: 946-955

Maccarrone M, Fiorucci L, Erba F, Bari M, Finazzi-Agro A, Ascoli F (2000) Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors. FEBS Lett 468: 176-180

Maccarrone M, Gubellini P, Bari M, Picconi B, Battista N, Centonze D, Bernardi G, Finazzi-Agro A, Calabresi P (2003) Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism. J Neurochem 85: 1018-1025

Maccarrone M, Lorenzon T, Bari M, Melino G, Finazzi-Agro A (2000) Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. J Biol Chem 275: 31938-31945

Maccarrone M, Pauselli R, Di Rienzo M, Finazzi-Agro A (2002) Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. Biochem J 366: 137-144

Maccarrone M, Piccirilli S, Bari M, Del Duca C, Finazzi-Agro A, Bagetta G (2003) Role of the endocannabinoid system in the in vivo neurotoxicity of the HIV-1 coat glycoprotein gp120. Journal of Neurochemistry 87: 130-130

Maccarrone M, Salvati S, Bari M, Finazzi A (2000) Anandamide and 2-arachidonoylglycerol inhibit fatty acid amide hydrolase by activating the lipoxygenase pathway of the arachidonate cascade. Biochem Biophys Res Commun 278: 576-583

Maccarrone M, Valensise H, Bari M, Lazzarin N, Romanini C, Finazzi-Agro A (2000) Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage. Lancet 355: 1326-1329

Maccarrone M, Valensise H, Bari M, Lazzarin N, Romanini C, Finazzi-Agro A (2001) Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. J Immunol 166: 7183-7189

Maccarrone M, Valverde O, Barbaccia ML, Castane A, Maldonado R, Ledent C, Parmentier M, Finazzi-Agro A (2002) Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. Eur J Neurosci 15: 1178-1186

Maccarrone M, van der Stelt M, Rossi A, Veldink GA, Vliegenthart JF, Agro AF (1998) Anandamide hydrolysis by human cells in culture and brain. J Biol Chem 273: 32332-32339

Maccarrone M, van der Stelt M, Veldink GA, Finazzi-Agro A (2002) Inhibitors of endocannabinoid degradation as potential therapeutic agents. Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents 1: 103-113

Mace SR, Dean JG, Murphy JR, Rhodes JL, Kuruvilla HG (2000) PACAP-38 is a chemorepellent and an agonist for the lysozyme receptor in tetrahymena thermophila. J Comp Physiol [A] 186: 39-43

MacKenzie AB, Mahaut-Smith MP, Sage SO (1996) Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets. J Biol Chem 271: 2879-2881

Mackenzie L, Bootman MD, Berridge MJ, Lipp P (2001) Predetermined recruitment of calcium release sites underlies excitation-contraction coupling in rat atrial myocytes. J Physiol 530: 417-429

Mackenzie L, Bootman MD, Laine M, Berridge MJ, Thuring J, Holmes A, Li WH, Lipp P (2002) The role of inositol 1,4,5-trisphosphate receptors in Ca(2+) signalling and the generation of arrhythmias in rat atrial myocytes. J Physiol 541: 395-409

Mackie K, Devane WA, Hille B (1993) Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells. Mol Pharmacol 44: 498-503

Mackie K, Lai Y, Westenbroek R, Mitchell R (1995) Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor. J Neurosci 15: 6552-6561

MacKrill JJ (1999) Protein-protein interactions in intracellular Ca2+-release channel function. Biochem J 337 (Pt 3): 345-361

MacLennan SJ, Reynen PH, Kwan J, Bonhaus DW (1998) Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB1 and CB2 receptors. Br J Pharmacol 124: 619-622

Macpherson AM, Archer DF, Leslie S, Charnock-Jones DS, Makkink WK, Smith SK (1999) The effect of etonogestrel on VEGF, oestrogen and progesterone receptor immunoreactivity and endothelial cell number in human endometrium. Hum Reprod 14: 3080-3087

Maeda N, Kawasaki T, Nakade S, Yokota N, Taguchi T, Kasai M, Mikoshiba K (1991) Structural and functional characterization of inositol 1,4,5-trisphosphate receptor channel from mouse cerebellum. J Biol Chem 266: 1109-1116

Maejima T, Hashimoto K, Yoshida T, Aiba A, Kano M (2001) Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors. Neuron 31: 463-475

Maguire G, Simko H, Weinreb RN, Ayoub G (1998) Transport-mediated release of endogenous glutamate in the vertebrate retina. Pflugers Arch 436: 481-484

Maguire JJ (2003) Discovering orphan receptor function using human in vitro pharmacology. Curr Opin Pharmacol 3: 135-139

Maguire JJ, Davenport AP (2002) Is urotensin-II the new endothelin? Br J Pharmacol 137: 579-588

Maguire JJ, Kuc RE, Davenport AP (2000) Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1. Br J Pharmacol 131: 441-446

Maguire JJ, Kuc RE, Davenport AP (2001) Vasoconstrictor activity of novel endothelin peptide, ET-1(1 - 31), in human mammary and coronary arteries in vitro. Br J Pharmacol 134: 1360-1366

Maguire JJ, Yu JC, Davenport AP (2002) ETA receptor antagonists inhibit intimal smooth muscle cell proliferation in human vessels. Clin Sci (Lond) 103 Suppl 48: 184S-188S

Mahadevan A, Siegel C, Martin BR, Abood ME, Beletskaya I, Razdan RK (2000) Novel cannabinol probes for CB1 and CB2 cannabinoid receptors. J Med Chem 43: 3778-3785

Mahaut-Smith MP, Ennion SJ, Rolf MG, Evans RJ (2000) ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets. Br J Pharmacol 131: 108-114

Mahony D, Weis FM, Massague J, Gurdon JB (1998) XTrR-I is a TGFbeta receptor and overexpression of truncated form of the receptor inhibits axis formation and dorsalising activity. Mech Dev 75: 95-105

Maingret F, Patel AJ, Lazdunski M, Honore E (2001) The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. Embo J 20: 47-54

Majerus ME, Mundy NI (2003) Mammalian melanism: natural selection in black and white. Trends Genet 19: 585-588

Mak DO, Foskett JK (1997) Single-channel kinetics, inactivation, and spatial distribution of inositol trisphosphate (IP3) receptors in Xenopus oocyte nucleus. J Gen Physiol 109: 571-587

Mak DO, McBride S, Foskett JK (1998) Inositol 1,4,5-trisphosphate [correction of tris-phosphate] activation of inositol trisphosphate [correction of tris-phosphate] receptor Ca2+ channel by ligand tuning of Ca2+ inhibition. Proc Natl Acad Sci U S A 95: 15821-15825

Makkerh JP, Dingwall C, Laskey RA (1996) Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids. Curr Biol 6: 1025-1027

Malan TP, Jr., Ibrahim MM, Deng H, Liu Q, Mata HP, Vanderah T, Porreca F, Makriyannis A (2001) CB2 cannabinoid receptor-mediated peripheral antinociception. Pain 93: 239-245

Malan TP, Jr., Ibrahim MM, Lai J, Vanderah TW, Makriyannis A, Porreca F (2003) CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? Curr Opin Pharmacol 3: 62-67

Malbrel PH, Monbrun C, Anselin D (1978) [Effect of combination of sulfothiorine and calcium pantothenate on the quality of the lacrimal film and its application to contact lenses]. Bull Soc Ophtalmol Fr 78: 643-645

Maldonado R (2002) Study of cannabinoid dependence in animals. Pharmacol Ther 95: 153-164

Maldonado R, Rodriguez de Fonseca F (2002) Cannabinoid addiction: behavioral models and neural correlates. J Neurosci 22: 3326-3331

Malinowska B, Godlewski G, Bucher B, Schlicker E (1997) Cannabinoid CB1 receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat. Naunyn Schmiedebergs Arch Pharmacol 356: 197-202

Malinowska B, Kwolek G, Gothert M (2001) Anandamide and methanandamide induce both vanilloid VR1- and cannabinoid CB1 receptor-mediated changes in heart rate and blood pressure in anaesthetized rats. Naunyn Schmiedebergs Arch Pharmacol 364: 562-569

Malinowska B, Piszcz J, Koneczny B, Hryniewicz A, Schlicker E (2001) Modulation of the cardiac autonomic transmission of pithed rats by presynaptic opioid OP4 and cannabinoid CB1 receptors. Naunyn Schmiedebergs Arch Pharmacol 364: 233-241

Mallet PE, Beninger RJ (1998) The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by delta9-tetrahydrocannabinol or anandamide. Psychopharmacology (Berl) 140: 11-19

Mallet PE, Beninger RJ (1998) Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. Life Sci 62: 2431-2439

Malone DT, Taylor DA (1998) Modulation of delta9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat. Br J Pharmacol 124: 1419-1424

Malone DT, Taylor DA (1999) Modulation by fluoxetine of striatal dopamine release following Delta9-tetrahydrocannabinol: a microdialysis study in conscious rats. Br J Pharmacol 128: 21-26

Mammano F, Frolenkov GI, Lagostena L, Belyantseva IA, Kurc M, Dodane V, Colavita A, Kachar B (1999) ATP-Induced Ca(2+) release in cochlear outer hair cells: localization of an inositol triphosphate-gated Ca(2+) store to the base of the sensory hair bundle. J Neurosci 19: 6918-6929

Manahan CL, Patnana M, Blumer KJ, Linder ME (2000) Dual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae. Mol Biol Cell 11: 957-968

Manallack DT, Pitt WR, Gancia E, Montana JG, Livingstone DJ, Ford MG, Whitley DC (2002) Selecting screening candidates for kinase and G protein-coupled receptor targets using neural networks. J Chem Inf Comput Sci 42: 1256-1262

Manallack DT, Tehan BG, Gancia E, Hudson BD, Ford MG, Livingstone DJ, Whitley DC, Pitt WR (2003) A consensus neural network-based technique for discriminating soluble and poorly soluble compounds. J Chem Inf Comput Sci 43: 674-679

Manara L, Croci T, Guagnini F, Rinaldi-Carmona M, Maffrand JP, Le Fur G, Mukenge S, Ferla G (2002) Functional assessment of neuronal cannabinoid receptors in the muscular layers of human ileum and colon. Dig Liver Dis 34: 262-269

Mancinelli R, Fabrizi A, Del Monaco S, Azzena GB, Vargiu R, Colombo GC, Gessa GL (2001) Inhibition of peristaltic activity by cannabinoids in the isolated distal colon of mouse. Life Sci 69: 101-111

Mandavilli A (2003) Marijuana researchers reach for pot of gold. Nat Med 9: 1227

Maneuf YP, Hughes J, McKnight AT (2001) Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices. Pain 93: 191-196

Maneuf YP, McKnight AT (2001) Calcitonin gene-related peptide-mediated increase in K(+)-induced [(3)H]-dopamine release from rat caudal striatal slices. Neurosci Lett 310: 73-76

Mang CF, Erbelding D, Kilbinger H (2001) Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors. Br J Pharmacol 134: 161-167

Mann F, Miranda E, Weinl C, Harmer E, Holt CE (2003) B-type Eph receptors and ephrins induce growth cone collapse through distinct intracellular pathways. J Neurobiol 57: 323-336

Mann F, Ray S, Harris W, Holt C (2002) Topographic mapping in dorsoventral axis of the Xenopus retinotectal system depends on signaling through ephrin-B ligands. Neuron 35: 461-473

Mansbach RS, Rovetti CC, Winston EN, Lowe JA, 3rd (1996) Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats. Psychopharmacology (Berl) 124: 315-322

Maranto AR (1994) Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium. J Biol Chem 269: 1222-1230

Marchand J, Bord A, Penarier G, Laure F, Carayon P, Casellas P (1999) Quantitative method to determine mRNA levels by reverse transcriptase-polymerase chain reaction from leukocyte subsets purified by fluorescence-activated cell sorting: application to peripheral cannabinoid receptors. Cytometry 35: 227-234

Marchant JS, Beecroft MD, Riley AM, Jenkins DJ, Marwood RD, Taylor CW, Potter BV (1997) Disaccharide polyphosphates based upon adenophostin A activate hepatic D-myo-inositol 1,4,5-trisphosphate receptors. Biochemistry 36: 12780-12790

Marchant JS, Parker I (1998) Kinetics of elementary Ca2+ puffs evoked in Xenopus oocytes by different Ins(1,4,5)P3 receptor agonists. Biochem J 334 (Pt 3): 505-509

Marchant JS, Taylor CW (1997) Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity. Curr Biol 7: 510-518

Marchese G, Casti P, Ruiu S, Saba P, Sanna A, Casu G, Pani L (2003) Haloperidol, but not clozapine, produces dramatic catalepsy in Delta9-THC-treated rats: possible clinical implications. Br J Pharmacol 140: 520-526

Margtich VM, Zhukov AD, Artamonov MV, Gulaya NM (1999) Convenient laboratory method of the labeled N-((1-14C)-palmitoyl)ethanolamine synthesis. Ukrainskii Biokhimicheskii Zhurnal 71: 108-110

Marhitykh VM, Zhukov OD, Artamonov MV, Hula NM (1999) [A convenient method for laboratory synthesis of the N-([1-14C]palmitoyl)ethanolamine, labeled by a fatty acid]. Ukr Biokhim Zh 71: 108-110

Marinelli S, Berretta N, Bernardi G, Mercuri NB (2002) Presynaptic Effects of Vr1 Activation in the Ventral Midbrain. Society for Neuroscience Abstract Viewer and Itinerary Planner 2002

Marinelli S, Di Marzo V, Berretta N, Matias I, Maccarrone M, Bernardi G, Mercuri NB (2003) Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors. J Neurosci 23: 3136-3144

Markey SP, Dudding T, Wang TC (2000) Base- and acid-catalyzed interconversions of O-acyl- and N-acyl-ethanolamines: a cautionary note for lipid analyses. J Lipid Res 41: 657-662

Marshall CJ (1994) MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Genet Dev 4: 82-89

Marshall CJ (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80: 179-185

Marshall LA, Hall RH, Winkler JD, Badger A, Bolognese B, Roshak A, Flamberg PL, Sung CM, Chabot-Fletcher M, Adams JL, et al. (1995) SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock. J Pharmacol Exp Ther 274: 1254-1262

Marsicano G, Goodenough S, Monory K, Hermann H, Eder M, Cannich A, Azad SC, Cascio M, Ortega Gutierrez S, van der Stelt M, Lopez-Rodriguez M, Casanova E, Schutz G, Zieglgansberger W, Di Marzo V, Lutz B (2003) The endocannabinoid system in principal forebrain neurones protects against excitotoxicity. Society for Neuroscience Abstract Viewer and Itinerary Planner 2003

Marsicano G, Goodenough S, Monory K, Hermann H, Eder M, Cannich A, Azad SC, Cascio MG, Gutierrez SO, van der Stelt M, Lopez-Rodriguez ML, Casanova E, Schutz G, Zieglgansberger W, Di Marzo V, Behl C, Lutz B (2003) CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 302: 84-88

Marsicano G, Lutz B (1999) Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. Eur J Neurosci 11: 4213-4225

Marsicano G, Moosmann B, Hermann H, Lutz B, Behl C (2002) Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J Neurochem 80: 448-456

Marsicano G, Wotjak CT, Azad SC, Bisogno T, Rammes G, Cascio MG, Hermann H, Tang J, Hofmann C, Zieglgansberger W, Di Marzo V, Lutz B (2002) The endogenous cannabinoid system controls extinction of aversive memories. Nature 418: 530-534

Martellotta MC, Cossu G, Fattore L, Gessa GL, Fratta W (1998) Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice. Neuroscience 85: 327-330

Martensson IL, Rolink A, Melchers F, Mundt C, Licence S, Shimizu T (2002) The pre-B cell receptor and its role in proliferation and Ig heavy chain allelic exclusion. Semin Immunol 14: 335-342

Martin-Bermudo MD (2000) Integrins modulate the Egfr signaling pathway to regulate tendon cell differentiation in the Drosophila embryo. Development 127: 2607-2615

Martin-Bermudo MD, Brown NH (2000) The localized assembly of extracellular matrix integrin ligands requires cell-cell contact. J Cell Sci 113 Pt 21: 3715-3723

Martin-Blanco E, Roch F, Noll E, Baonza A, Duffy JB, Perrimon N (1999) A temporal switch in DER signaling controls the specification and differentiation of veins and interveins in the Drosophila wing. Development 126: 5739-5747

Martin BR, Beletskaya I, Patrick G, Jefferson R, Winckler R, Deutsch DG, Di Marzo V, Dasse O, Mahadevan A, Razdan RK (2000) Cannabinoid properties of methylfluorophosphonate analogs. J Pharmacol Exp Ther 294: 1209-1218

Martin BR, Jefferson RG, Winckler R, Wiley JL, Thomas BF, Crocker PJ, Williams W, Razdan RK (2002) Assessment of structural commonality between tetrahydrocannabinol and anandamide. Eur J Pharmacol 435: 35-42

Martin BR, Lichtman AH (1998) Cannabinoid transmission and pain perception. Neurobiol Dis 5: 447-461

Martin BR, Mechoulam R, Razdan RK (1999) Discovery and characterization of endogenous cannabinoids. Life Sci 65: 573-595

Martin C, Ashley R, Shoshan-Barmatz V (1993) The effect of local anaesthetics on the ryanodine receptor/Ca2+ release channel of brain microsomal membranes. FEBS Lett 328: 77-81

Martin M, Ledent C, Parmentier M, Maldonado R, Valverde O (2002) Involvement of CB1 cannabinoid receptors in emotional behaviour. Psychopharmacology (Berl) 159: 379-387

Martin RS, Luong LA, Welsh NJ, Eglen RM, Martin GR, MacLennan SJ (2000) Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human. Br J Pharmacol 129: 1707-1715

Martin RS, Reynen PH, Calixto JJ, Reyes CL, Chang TK, Dietrich PS, Bonhaus DW, MacLennan SJ (2002) Pharmacological comparison of a recombinant CB1 cannabinoid receptor with its G(alpha 16) fusion product. J Biomol Screen 7: 281-289

Martin WJ, Loo CM, Basbaum AI (1999) Spinal cannabinoids are anti-allodynic in rats with persistent inflammation. Pain 82: 199-205

Martinez-Orgado J, Fernandez-Frutos B, Gonzalez R, Romero E, Uriguen L, Romero J, Viveros MP (2003) Neuroprotection by the cannabinoid agonist WIN-55212 in an in vivo newborn rat model of acute severe asphyxia. Brain Res Mol Brain Res 114: 132-139

Martinez-Pinna J, Tolhurst G, Gurung IS, Vandenberg JI, Mahaut-Smith MP (2004) Sensitivity limits for voltage control of P2Y receptor-evoked Ca2+ mobilization in the rat megakaryocyte. J Physiol 555: 61-70

Martinez-Vargas M, Murillo-Rodriguez E, Gonzalez-Rivera R, Landa A, Mendez-Diaz M, Prospro-Garcia O, Navarro L (2003) Sleep modulates cannabinoid receptor 1 expression in the pons of rats. Neuroscience 117: 197-201

Marty A, Evans MG, Tan YP, Trautmann A (1986) Muscarinic response in rat lacrimal glands. J Exp Biol 124: 15-32

Marty A, Tan YP (1989) The initiation of calcium release following muscarinic stimulation in rat lacrimal glands. J Physiol 419: 665-687

Marty A, Tan YP, Trautmann A (1984) Three types of calcium-dependent channel in rat lacrimal glands. J Physiol 357: 293-325

Marty A, Zimmerberg J (1989) Diffusion into the patch-clamp recording pipette of a factor necessary for muscarinic current response. Cell Signal 1: 259-268

Maruyama I, Wang Y, Liu Y, Yamaji K, Sarker KP, Abeyama K, Wada H, Hashiguchi T (2003) Activated protein C (APC) inhibits lipopolysaccharide (LPS)-induced anandamide and 2-arachidonylglycerol generation in vitro and in vivo: A possible mechanism of improving of severe septic patients by APC. Blood 102

Marzo VD, Bisogno T, De Petrocellis L (2001) Endocannabinoids Part II: pathological CNS conditions involving the endocannabinoid system and their possible treatment with endocannabinoid-based drugs. Expert Opin Ther Targets 5: 349-362

Mascolo N, Izzo AA, Ligresti A, Costagliola A, Pinto L, Cascio MG, Maffia P, Cecio A, Capasso F, Di Marzo V (2002) The endocannabinoid system and the molecular basis of paralytic ileus in mice. Faseb J 16: 1973-1975

Maslov LN, Lasukova OV, Krylatov AV, Lishmanov Iu B, Pertwee R (2003) [Alterations of inotropic function of isolated heart and extent of injury of cardiomyocytes after cannabinoid receptor activation during ischemia and reperfusion]. Ross Fiziol Zh Im I M Sechenova 89: 1108-1116

Maslov LN, Lishmanov Iu B, Maismekulova LA, Mechoulam P (2001) [Antiarrhythmic properties of a cannabinoid (CB) receptor agonist]. Eksp Klin Farmakol 64: 37-40

Mason DJ, Jr., Lowe J, Welch SP (1999) Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception. Eur J Pharmacol 378: 237-248

Mason MJ, Mahaut-Smith MP (2001) Voltage-dependent Ca2+ release in rat megakaryocytes requires functional IP3 receptors. J Physiol 533: 175-183

Mason S, Smart D, Marshall IC, McKnight A, Skepper JN, McNulty S (2002) Identification and characterisation of functional bombesin receptors in human astrocytes. Eur J Pharmacol 438: 25-34

Mason SL, Ho M, Nicholson J, McKnight AT (2001) In vitro characterization of Ac-RYYRWK-NH(2), Ac-RYYRIK-NH(2) and [Phe1Psi(CH(2)-NH)Gly2] nociceptin(1-13)NH(2) at rat native and recombinant ORL(1) receptors. Neuropeptides 35: 244-256

Massa F, Marsicano G, Hermann H, Cannich A, Monory K, Cravatt BF, Ferri GL, Sibaev A, Storr M, Lutz B (2004) The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest 113: 1202-1209

Massa SM, Xie Y, Longo FM (2002) Alzheimer's therapeutics: neurotrophin small molecule mimetics. J Mol Neurosci 19: 107-111

Masserano JM, Karoum F, Wyatt RJ (1999) SR 141716A, a CB1 cannabinoid receptor antagonist, potentiates the locomotor stimulant effects of amphetamine and apomorphine. Behav Pharmacol 10: 429-432

Massi P, Vaccani A, Ceruti S, Colombo A, Abbracchio MP, Parolaro D (2004) Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. J Pharmacol Exp Ther 308: 838-845

Massi P, Vaccani A, Romorini S, Parolaro D (2001) Comparative characterization in the rat of the interaction between cannabinoids and opiates for their immunosuppressive and analgesic effects. J Neuroimmunol 117: 116-124

Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci U S A 82: 4245-4249

Matias I, Bisogno T, Melck D, Vandenbulcke F, Verger-Bocquet M, De Petrocellis L, Sergheraert C, Breton C, Di Marzo V, Salzet M (2001) Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis. Brain Res Mol Brain Res 87: 145-159

Matias I, Chen J, De Petrocellis L, Bisogno T, Ligresti A, Fezza F, Krauss AH, Shi L, Protzman CE, Li C, Liang Y, Nieves AL, Kedzie KM, Burk RM, Di Marzo V, Woodward DF (2004) Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism. J Pharmacol Exp Ther 309: 745-757

Matias I, Leonhardt M, Lesage J, De Petrocellis L, Dupouy JP, Vieau D, Di Marzo V (2003) Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. Cell Mol Life Sci 60: 382-389

Matias I, Leonhardt M, Lesage J, De Petrocellis L, Dupouy JP, Vieau D, Di Marzo V (2003) Effect of maternal under nutrition on pup body weight and hypothalamic endocannabinoid levels. Cellular and Molecular Life Sciences 60: 382-389

Matias I, Pochard P, Orlando P, Salzet M, Pestel J, Di Marzo V (2002) Presence and regulation of the endocannabinoid system in human dendritic cells. Eur J Biochem 269: 3771-3778

Mato S, Del Olmo E, Pazos A (2003) Ontogenetic development of cannabinoid receptor expression and signal transduction functionality in the human brain. Eur J Neurosci 17: 1747-1754

Mato S, Pazos A (2004) Influence of age, postmortem delay and freezing storage period on cannabinoid receptor density and functionality in human brain. Neuropharmacology 46: 716-726

Matrisciano F, Storto M, Ngomba RT, Cappuccio I, Caricasole A, Scaccianoce S, Riozzi B, Melchiorri D, Nicoletti F (2002) Imipramine treatment up-regulates the expression and function of mGlu2/3 metabotropic glutamate receptors in the rat hippocampus. Neuropharmacology 42: 1008-1015

Matsuda K, Hirasawa H, Oda S, Shiga H, Nakanishi K, Nakamura M (2002) [Endotoxin removal in septic shock]. Nippon Geka Gakkai Zasshi 103: 880-886

Matsuda LA (1997) Molecular aspects of cannabinoid receptors. Crit Rev Neurobiol 11: 143-166

Matsuda S, Kanemitsu N, Nakamura A, Mimura Y, Ueda N, Kurahashi Y, Yamamoto S (1997) Metabolism of anandamide, an endogenous cannabinoid receptor ligand, in porcine ocular tissues. Exp Eye Res 64: 707-711

Matsunaga I, Yamada M, Kusunose E, Miki T, Ichihara K (1998) Further characterization of hydrogen peroxide-dependent fatty acid alpha-hydroxylase from Sphingomonas paucimobilis. J Biochem (Tokyo) 124: 105-110

Matsunaga I, Yokotani N, Gotoh O, Kusunose E, Yamada M, Ichihara K (1997) Molecular cloning and expression of fatty acid alpha-hydroxylase from Sphingomonas paucimobilis. J Biol Chem 272: 23592-23596

Matthews HR, Reisert J (2003) Calcium, the two-faced messenger of olfactory transduction and adaptation. Curr Opin Neurobiol 13: 469-475

Matveyeva M, Hartmann CB, Harrison MT, Cabral GA, McCoy KL (2000) Delta(9)-tetrahydrocannabinol selectively increases aspartyl cathepsin D proteolytic activity and impairs lysozyme processing by macrophages. Int J Immunopharmacol 22: 373-381

Mauduit P, Herman G, Dreux C, Rossignol B (1988) [In vitro effect of pentoxifylline on the metabolism of glycogen and the secretory process in the parotid and lacrimal extraorbital glands in rats]. Pathol Biol (Paris) 36: 1060-1065

Mauduit P, Herman G, Rossignol B (1983) Effect of trifluoperazine on 3H-labeled protein secretion induced by pentoxifylline, cholinergic or adrenergic agonists in rat lacrimal gland. A possible role of calmodulin? FEBS Lett 152: 207-211

Mauduit P, Herman G, Rossignol B (1984) Protein secretion induced by isoproterenol or pentoxifylline in lacrimal gland: Ca2+ effects. Am J Physiol 246: C37-44

Mauduit P, Herman G, Rossignol B (1987) Newly synthesized protein secretion in rat lacrimal gland: post-second messenger synergism. Am J Physiol 253: C514-524

Mauduit P, Jammes H, Rossignol B (1993) M3 muscarinic acetylcholine receptor coupling to PLC in rat exorbital lacrimal acinar cells. Am J Physiol 264: C1550-1560

Mauduit P, Zoukhri D, Rossignol B (1989) Direct activation of a protein kinase activity from rat lacrimal gland by PMA in a phospholipid-free system. FEBS Lett 252: 5-11

Mauler F, Hinz V, Augstein KH, Fassbender M, Horvath E (2003) Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271. Brain Res 989: 99-111

Mauler F, Horvath E, De Vry J, Jager R, Schwarz T, Sandmann S, Weinz C, Heinig R, Bottcher M (2003) BAY 38-7271: a novel highly selective and highly potent cannabinoid receptor agonist for the treatment of traumatic brain injury. CNS Drug Rev 9: 343-358

Mauler F, Mittendorf J, Horvath E, De Vry J (2002) Characterization of the diarylether sulfonylester (-)-(R)-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective properties. J Pharmacol Exp Ther 302: 359-368

Maurelli S, Bisogno T, De Petrocellis L, Di Luccia A, Marino G, Di Marzo V (1995) Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma 'anandamide amidohydrolase'. FEBS Lett 377: 82-86

Mazzari S, Canella R, Petrelli L, Marcolongo G, Leon A (1996) N-(2-hydroxyethyl)hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation. Eur J Pharmacol 300: 227-236

Mazzola C, Micale V, Drago F (2003) Amnesia induced by beta-amyloid fragments is counteracted by cannabinoid CB1 receptor blockade. Eur J Pharmacol 477: 219-225

McAllister SD, Glass M (2002) CB(1) and CB(2) receptor-mediated signalling: a focus on endocannabinoids. Prostaglandins Leukot Essent Fatty Acids 66: 161-171

McAllister SD, Griffin G, Satin LS, Abood ME (1999) Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system. J Pharmacol Exp Ther 291: 618-626

McAllister SD, Rizvi G, Anavi-Goffer S, Hurst DP, Barnett-Norris J, Lynch DL, Reggio PH, Abood ME (2003) An aromatic microdomain at the cannabinoid CB(1) receptor constitutes an agonist/inverse agonist binding region. J Med Chem 46: 5139-5152

McAndrew RS, Chapman KD (1998) Enzymology of cottonseed microsomal N-acylphosphatidylethanolamine synthase: kinetic properties and mechanism-based inactivation. Biochim Biophys Acta 1390: 21-36

McCarron RM, Shohami E, Panikashvili D, Chen Y, Golech S, Strasser A, Mechoulam R, Spatz M (2003) Antioxidant properties of the vasoactive endocannabinoid, 2-arachidonoyl glycerol (2-AG). Acta Neurochir Suppl 86: 271-275

McCoy KL, Matveyeva M, Carlisle SJ, Cabral GA (1999) Cannabinoid inhibition of the processing of intact lysozyme by macrophages: evidence for CB2 receptor participation. J Pharmacol Exp Ther 289: 1620-1625

McCulloch AI, Randall MD (1998) Sex differences in the relative contributions of nitric oxide and EDHF to agonist-stimulated endothelium-dependent relaxations in the rat isolated mesenteric arterial bed. Br J Pharmacol 123: 1700-1706

McDonald AJ, Mascagni F (2001) Localization of the CB1 type cannabinoid receptor in the rat basolateral amygdala: high concentrations in a subpopulation of cholecystokinin-containing interneurons. Neuroscience 107: 641-652

McGeer PL, McGeer EG (2001) Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging 22: 799-809

McGregor IS, Arnold JC, Weber MF, Topple AN, Hunt GE (1998) A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. Brain Res 802: 19-26

McGregor IS, Dastur FN, McLellan RA, Brown RE (1996) Cannabinoid modulation of rat pup ultrasonic vocalizations. Eur J Pharmacol 313: 43-49

McGuire JJ, Ding H, Triggle CR (2001) Endothelium-derived relaxing factors: a focus on endothelium-derived hyperpolarizing factor(s). Can J Physiol Pharmacol 79: 443-470

McIntosh HH, Song C, Howlett AC (1998) CB1 cannabinoid receptor: cellular regulation and distribution in N18TG2 neuroblastoma cells. Brain Res Mol Brain Res 53: 163-173

McIntosh JM, Ghomashchi F, Gelb MH, Dooley DJ, Stoehr SJ, Giordani AB, Naisbitt SR, Olivera BM (1995) Conodipine-M, a novel phospholipase A2 isolated from the venom of the marine snail Conus magus. J Biol Chem 270: 3518-3526

McKallip RJ, Lombard C, Fisher M, Martin BR, Ryu S, Grant S, Nagarkatti PS, Nagarkatti M (2002) Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood 100: 627-634

McKinney MK, Cravatt BF (2003) Evidence for distinct roles in catalysis for residues of the serine-serine-lysine catalytic triad of fatty acid amide hydrolase. J Biol Chem 278: 37393-37399

McLatchie LM, Bevan S (2001) The effects of pH on the interaction between capsaicin and the vanilloid receptor in rat dorsal root ganglia neurons. Br J Pharmacol 132: 899-908

McLaughlin PJ, Winston K, Swezey L, Wisniecki A, Aberman J, Tardif DJ, Betz AJ, Ishiwari K, Makriyannis A, Salamone JD (2003) The cannabinoid CB1 antagonists SR 141716A and AM 251 suppress food intake and food-reinforced behavior in a variety of tasks in rats. Behav Pharmacol 14: 583-588

McLaughlin SH, Smith HW, Jackson SE (2002) Stimulation of the weak ATPase activity of human hsp90 by a client protein. J Mol Biol 315: 787-798

McMahan UJ (1990) The agrin hypothesis. Cold Spring Harb Symp Quant Biol 55: 407-418

McMahan UJ, Horton SE, Werle MJ, Honig LS, Kroger S, Ruegg MA, Escher G (1992) Agrin isoforms and their role in synaptogenesis. Curr Opin Cell Biol 4: 869-874

McMurray RW, Hardy KJ (2002) Cox-2 inhibitors: today and tomorrow. Am J Med Sci 323: 181-189

McNulty TJ, Letcher AJ, Dawson AP, Irvine RF (2001) Tissue distribution of GAP1(IP4BP) and GAP1(m): two inositol 1,3,4,5-tetrakisphosphate-binding proteins. Cell Signal 13: 877-886

McNulty TJ, Taylor CW (1999) Extracellular heavy-metal ions stimulate Ca2+ mobilization in hepatocytes. Biochem J 339 (Pt 3): 555-561

McPartland J, Di Marzo V, De Petrocellis L, Mercer A, Glass M (2001) Cannabinoid receptors are absent in insects. J Comp Neurol 436: 423-429

McPartland JM (2004) Phylogenomic and chemotaxonomic analysis of the endocannabinoid system. Brain Res Brain Res Rev 45: 18-29

McPartland JM, Glass M (2003) Functional mapping of cannabinoid receptor homologs in mammals, other vertebrates, and invertebrates. Gene 312: 297-303

McQuibban GA, Saurya S, Freeman M (2003) Mitochondrial membrane remodelling regulated by a conserved rhomboid protease. Nature 423: 537-541

McVey DC, Schmid PC, Schmid HH, Vigna SR (2003) Endocannabinoids induce ileitis in rats via the capsaicin receptor (VR1). J Pharmacol Exp Ther 304: 713-722

Mechoulam R (1997) Todd's achievement. Nature 386: 755

Mechoulam R (1999) Recent advantages in cannabinoid research. Forsch Komplementarmed 6 Suppl 3: 16-20

Mechoulam R (2002) Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression. Prostaglandins Leukot Essent Fatty Acids 66: 93-99

Mechoulam R, Ben-Shabat S (1999) From gan-zi-gun-nu to anandamide and 2-arachidonoylglycerol: the ongoing story of cannabis. Nat Prod Rep 16: 131-143

Mechoulam R, Ben-Shabat S, Hanus L, Ligumsky M, Kaminski NE, Schatz AR, Gopher A, Almog S, Martin BR, Compton DR, et al. (1995) Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 50: 83-90

Mechoulam R, Ben Shabat S, Hanus L, Fride E, Vogel Z, Bayewitch M, Sulcova AE (1996) Endogenous cannabinoid ligands--chemical and biological studies. J Lipid Mediat Cell Signal 14: 45-49

Mechoulam R, Fride E (2001) Physiology. A hunger for cannabinoids. Nature 410: 763, 765

Mechoulam R, Fride E, Ben-Shabat S, Meiri U, Horowitz M (1998) Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid. Eur J Pharmacol 362: R1-3

Mechoulam R, Fride E, Di Marzo V (1998) Endocannabinoids. Eur J Pharmacol 359: 1-18

Mechoulam R, Fride E, Hanus L, Sheskin T, Bisogno T, Di Marzo V, Bayewitch M, Vogel Z (1997) Anandamide may mediate sleep induction. Nature 389: 25-26

Mechoulam R, Hanus L (2002) Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects. Chem Phys Lipids 121: 35-43

Mechoulam R, Hanus L, Martin BR (1994) Search for endogenous ligands of the cannabinoid receptor. Biochem Pharmacol 48: 1537-1544

Mechoulam R, Lichtman AH (2003) Neuroscience. Stout guards of the central nervous system. Science 302: 65-67

Mechoulam R, Panikashvili D, Shohami E (2002) Cannabinoids and brain injury: therapeutic implications. Trends Mol Med 8: 58-61

Mechoulam R, Parker L (2003) Cannabis and alcohol--a close friendship. Trends Pharmacol Sci 24: 266-268

Mechoulam R, Parker LA, Gallily R (2002) Cannabidiol: an overview of some pharmacological aspects. J Clin Pharmacol 42: 11S-19S

Mechoulam R, Spatz M, Shohami E (2002) Endocannabinoids and neuroprotection. Sci STKE 2002: RE5

Medina G, Sewter C, Puig AJ (2000) [PPARgamma and thiazolidinediones, something more than a treatment for diabetes]. Med Clin (Barc) 115: 392-397

Mehta MA, Manes FF, Magnolfi G, Sahakian BJ, Robbins TW (2004) Impaired set-shifting and dissociable effects on tests of spatial working memory following the dopamine D(2) receptor antagonist sulpiride in human volunteers. Psychopharmacology (Berl)

Mehta MA, Sahakian BJ, McKenna PJ, Robbins TW (1999) Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson's disease. Psychopharmacology (Berl) 146: 162-174

Meirhaeghe A, Luan J, Selberg-Franks P, Hennings S, Mitchell J, Halsall D, O'Rahilly S, Wareham NJ (2001) The effect of the Gly16Arg polymorphism of the beta(2)-adrenergic receptor gene on plasma free fatty acid levels is modulated by physical activity. J Clin Endocrinol Metab 86: 5881-5887

Meisner H, Daga A, Buxton J, Fernandez B, Chawla A, Banerjee U, Czech MP (1997) Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development. Mol Cell Biol 17: 2217-2225

Meissner G, Rios E, Tripathy A, Pasek DA (1997) Regulation of skeletal muscle Ca2+ release channel (ryanodine receptor) by Ca2+ and monovalent cations and anions. J Biol Chem 272: 1628-1638

Meissner G, Rousseau E, Lai FA, Liu QY, Anderson KA (1988) Biochemical characterization of the Ca2+ release channel of skeletal and cardiac sarcoplasmic reticulum. Mol Cell Biochem 82: 59-65

Melck D, Bisogno T, De Petrocellis L, Beaulieu P, Rice AS, Di Marzo V (2002) Cannabimimetic eicosanoids in cancer and inflammation: an update. Adv Exp Med Biol 507: 381-386

Melck D, Bisogno T, De Petrocellis L, Chuang H, Julius D, Bifulco M, Di Marzo V (1999) Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. Biochem Biophys Res Commun 262: 275-284

Melck D, De Petrocellis L, Orlando P, Bisogno T, Laezza C, Bifulco M, Di Marzo V (2000) Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. Endocrinology 141: 118-126

Melck D, Rueda D, Galve-Roperh I, De Petrocellis L, Guzman M, Di Marzo V (1999) Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. FEBS Lett 463: 235-240

Melikova MS, Filatova MM, Kornilova ES (2003) [Cbl--a polyfunctional regulator of cellular processes]. Tsitologiia 45: 1134-1148

Melis M, Gessa GL, Diana M (2000) Different mechanisms for dopaminergic excitation induced by opiates and cannabinoids in the rat midbrain. Prog Neuropsychopharmacol Biol Psychiatry 24: 993-1006

Melis M, Pistis M, Perra S, Muntoni AL, Pillolla G, Gessa GL (2004) Endocannabinoids mediate presynaptic inhibition of glutamatergic transmission in rat ventral tegmental area dopamine neurons through activation of CB1 receptors. J Neurosci 24: 53-62

Melis MR, Succu S, Mascia MS, Argiolas A (2004) Antagonism of cannabinoid CB1 receptors in the paraventricular nucleus of male rats induces penile erection. Neurosci Lett 359: 17-20

Mellor JR, Merlo D, Jones A, Wisden W, Randall AD (1998) Mouse cerebellar granule cell differentiation: electrical activity regulates the GABAA receptor alpha 6 subunit gene. J Neurosci 18: 2822-2833

Mellor JR, Wisden W, Randall AD (2000) Somato-synaptic variation of GABA(A) receptors in cultured murine cerebellar granule cells: investigation of the role of the alpha6 subunit. Neuropharmacology 39: 1495-1513

Melvin LS, Milne GM, Johnson MR, Wilken GH, Howlett AC (1995) Structure-activity relationships defining the ACD-tricyclic cannabinoids: cannabinoid receptor binding and analgesic activity. Drug Des Discov 13: 155-166

Mendelson WB, Basile AS (1999) The hypnotic actions of oleamide are blocked by a cannabinoid receptor antagonist. Neuroreport 10: 3237-3239

Mendelson WB, Basile AS (2001) The hypnotic actions of the fatty acid amide, oleamide. Neuropsychopharmacology 25: S36-39

Mendiguren A, Pineda J (2003) Modulation of NMDA - induced excitation of locus coeruleus neurons by cannabinoids in rat brain slices. Society for Neuroscience Abstract Viewer and Itinerary Planner 2003

Mendizabal VE, Orliac ML, Adler-Graschinsky E (2001) Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. Eur J Pharmacol 427: 251-262

Meng ID, Johansen JP (2004) Antinociception and modulation of rostral ventromedial medulla neuronal activity by local microinfusion of a cannabinoid receptor agonist. Neuroscience 124: 685-693

Meng S, Badrinarain J, Sibley E, Fang R, Hodin R (2001) Thyroid hormone and the d-type cyclins interact in regulating enterocyte gene transcription. J Gastrointest Surg 5: 49-55

Mereu G, Fa M, Ferraro L, Cagiano R, Antonelli T, Tattoli M, Ghiglieri V, Tanganelli S, Gessa GL, Cuomo V (2003) Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release. Proc Natl Acad Sci U S A 100: 4915-4920

Meschler JP, Howlett AC (1999) Thujone exhibits low affinity for cannabinoid receptors but fails to evoke cannabimimetic responses. Pharmacol Biochem Behav 62: 473-480

Meschler JP, Howlett AC (2001) Signal transduction interactions between CB1 cannabinoid and dopamine receptors in the rat and monkey striatum. Neuropharmacology 40: 918-926

Meschler JP, Kraichely DM, Wilken GH, Howlett AC (2000) Inverse agonist properties of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide HCl (SR141716A) and 1-(2-chlorophenyl)-4-cyano-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxyl ic acid phenylamide (CP-272871) for the CB(1) cannabinoid receptor. Biochem Pharmacol 60: 1315-1323

Mesenholler M, Matthews EK (2000) A key role for the mitochondrial benzodiazepine receptor in cellular photosensitisation with delta-aminolaevulinic acid. Eur J Pharmacol 406: 171-180

Messersmith EK, Redburn DA (1992) gamma-Aminobutyric acid immunoreactivity in multiple cell types of the developing rabbit retina. Vis Neurosci 8: 201-211

Michel AD, Kaur R, Chessell IP, Humphrey PP (2000) Antagonist effects on human P2X(7) receptor-mediated cellular accumulation of YO-PRO-1. Br J Pharmacol 130: 513-520

Michel AD, Xing M, Humphrey PP (2001) Serum constituents can affect 2'-& 3'-O-(4-benzoylbenzoyl)-ATP potency at P2X(7) receptors. Br J Pharmacol 132: 1501-1508

Michikawa T, Hirota J, Kawano S, Hiraoka M, Yamada M, Furuichi T, Mikoshiba K (1999) Calmodulin mediates calcium-dependent inactivation of the cerebellar type 1 inositol 1,4,5-trisphosphate receptor. Neuron 23: 799-808

Mignery GA, Newton CL, Archer BT, 3rd, Sudhof TC (1990) Structure and expression of the rat inositol 1,4,5-trisphosphate receptor. J Biol Chem 265: 12679-12685

Mignery GA, Sudhof TC, Takei K, De Camilli P (1989) Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor. Nature 342: 192-195

Mikawa Y, Matsuda S, Kanagawa T, Tajika T, Ueda N, Mimura Y (1997) Ocular activity of topically administered anandamide in the rabbit. Jpn J Ophthalmol 41: 217-220

Miles R (1999) Neurobiology. A homeostatic switch. Nature 397: 215-216

Millns PJ, Chapman V, Kendall DA (2002) Anandamide-evoked Ca2+ responses in adult rat dorsal root ganglion neurones. British Journal of Pharmacology 135

Mills J, Laurent Charest D, Lam F, Beyreuther K, Ida N, Pelech SL, Reiner PB (1997) Regulation of amyloid precursor protein catabolism involves the mitogen-activated protein kinase signal transduction pathway. J Neurosci 17: 9415-9422

Milton NG (2002) Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. Neurosci Lett 332: 127-130

Mimeault M, Pommery N, Wattez N, Bailly C, Henichart JP (2003) Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. Prostate 56: 1-12

Misgeld UA, Mades S, Yanovsky Y (2002) Dopaminergic Modulation of the Inhibitory Input to Substantia Nigra Neurons. Society for Neuroscience Abstract Viewer and Itinerary Planner 2002

Mistry H, Gitlin JM, Mitchell JA, Hiley CR (2003) Endothelium-dependent relaxation and endothelial hyperpolarization by P2Y receptor agonists in rat-isolated mesenteric artery. Br J Pharmacol 139: 661-671

Miyakawa T, Maeda A, Yamazawa T, Hirose K, Kurosaki T, Iino M (1999) Encoding of Ca2+ signals by differential expression of IP3 receptor subtypes. Embo J 18: 1303-1308

Miyawaki A, Furuichi T, Ryou Y, Yoshikawa S, Nakagawa T, Saitoh T, Mikoshiba K (1991) Structure-function relationships of the mouse inositol 1,4,5-trisphosphate receptor. Proc Natl Acad Sci U S A 88: 4911-4915

Miyazawa A, Fujiyoshi Y, Stowell M, Unwin N (1999) Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall. J Mol Biol 288: 765-786

Mo FM, Offertaler L, Kunos G (2004) Atypical cannabinoid stimulates endothelial cell migration via a Gi/Go-coupled receptor distinct from CB1, CB2 or EDG-1. Eur J Pharmacol 489: 21-27

Mochizuki T, Wu G, Hayashi T, Xenophontos SL, Veldhuisen B, Saris JJ, Reynolds DM, Cai Y, Gabow PA, Pierides A, Kimberling WJ, Breuning MH, Deltas CC, Peters DJ, Somlo S (1996) PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 272: 1339-1342

Moelling K, Schulze T, Knoop MT, Kay J, Jupp R, Nicolaou G, Pearl LH (1990) In vitro inhibition of HIV-1 proteinase by cerulenin. FEBS Lett 261: 373-377

Moesgaard B, Hansen HH, Hansen SL, Hansen SH, Petersen G, Hansen HS (2003) Brain levels of N-acylethanolamine phospholipids in mice during pentylenetetrazol-induced seizure. Lipids 38: 387-390

Moesgaard B, Petersen G, Jaroszewski JW, Hansen HS (2000) Age dependent accumulation of N-acyl-ethanolamine phospholipids in ischemic rat brain. A (31)P NMR and enzyme activity study. J Lipid Res 41: 985-990

Moesgaard B, Petersen G, Mortensen SA, Hansen HS (2002) Substantial species differences in relation to formation and degradation of N-acyl-ethanolamine phospholipids in heart tissue: an enzyme activity study. Comp Biochem Physiol B Biochem Mol Biol 131: 475-482

Moezi L, Rezayat M, Samini M, Shafaroodi H, Mehr SE, Ebrahimkhani MR, Dehpour AR (2004) Potentiation of anandamide effects in mesenteric beds isolated from bile duct-ligated rats: role of nitric oxide. Eur J Pharmacol 486: 53-59

Moffett-King A, Entrican G, Ellis S, Hutchinson J, Bainbridge D (2002) Natural killer cells and reproduction. Trends Immunol 23: 332-333

Mohle R, Bautz F, Denzlinger C, Kanz L (2001) Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. Ann N Y Acad Sci 938: 26-34; discussion 34-25

Molderings GJ, Bonisch H, Hammermann R, Gothert M, Bruss M (2002) Noradrenaline release-inhibiting receptors on PC12 cells devoid of alpha(2(-)) and CB(1) receptors: similarities to presynaptic imidazoline and edg receptors. Neurochem Int 40: 157-167

Molderings GJ, Gothert M (1998) Presynaptic imidazoline receptors mediate inhibition of noradrenaline release from sympathetic nerves in rat blood vessels. Fundam Clin Pharmacol 12: 388-397

Molderings GJ, Likungu J, Gothert M (1999) Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship. Naunyn Schmiedebergs Arch Pharmacol 360: 157-164

Moldrich G, Wenger T (2000) Localization of the CB1 cannabinoid receptor in the rat brain. An immunohistochemical study. Peptides 21: 1735-1742

Molina-Holgado E, Vela JM, Arevalo-Martin A, Almazan G, Molina-Holgado F, Borrell J, Guaza C (2002) Cannabinoids promote oligodendrocyte progenitor survival: involvement of cannabinoid receptors and phosphatidylinositol-3 kinase/Akt signaling. J Neurosci 22: 9742-9753

Molina-Holgado F, Lledo A, Guaza C (1997) Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. Neuroreport 8: 1929-1933

Molina-Holgado F, Molina-Holgado E, Guaza C (1998) The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. FEBS Lett 433: 139-142

Molina-Holgado F, Molina-Holgado E, Guaza C, Rothwell NJ (2002) Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures. J Neurosci Res 67: 829-836

Molina-Holgado F, Pinteaux E, Moore JD, Molina-Holgado E, Guaza C, Gibson RM, Rothwell NJ (2003) Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia. J Neurosci 23: 6470-6474

Mombouli JV, Schaeffer G, Holzmann S, Kostner GM, Graier WF (1999) Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells. Br J Pharmacol 126: 1593-1600

Moneer Z, Taylor CW (2002) Reciprocal regulation of capacitative and non-capacitative Ca2+ entry in A7r5 vascular smooth muscle cells: only the latter operates during receptor activation. Biochem J 362: 13-21

Mongan NP, Hughes IA, Lim HN (2002) Evidence that luteinising hormone receptor polymorphisms may contribute to male undermasculinisation. Eur J Endocrinol 147: 103-107

Mongan NP, Jaaskelainen J, Green K, Schwabe JW, Shimura N, Dattani M, Hughes IA (2002) Two de novo mutations in the AR gene cause the complete androgen insensitivity syndrome in a pair of monozygotic twins. J Clin Endocrinol Metab 87: 1057-1061

Monhemius R, Azami J, Green DL, Roberts MH (2001) CB1 receptor mediated analgesia from the Nucleus Reticularis Gigantocellularis pars alpha is activated in an animal model of neuropathic pain. Brain Res 908: 67-74

Monory K, Tzavara ET, Lexime J, Ledent C, Parmentier M, Borsodi A, Hanoune J (2002) Novel, not adenylyl cyclase-coupled cannabinoid binding site in cerebellum of mice. Biochem Biophys Res Commun 292: 231-235

Montanaro F, Gee SH, Jacobson C, Lindenbaum MH, Froehner SC, Carbonetto S (1998) Laminin and alpha-dystroglycan mediate acetylcholine receptor aggregation via a MuSK-independent pathway. J Neurosci 18: 1250-1260

Moody JS, Kozak KR, Ji C, Marnett LJ (2001) Selective oxygenation of the endocannabinoid 2-arachidonylglycerol by leukocyte-type 12-lipoxygenase. Biochemistry 40: 861-866

Moore D, Chambers J, Waldvogel H, Faull R, Emson P (2000) Regional and cellular distribution of the P2Y(1) purinergic receptor in the human brain: striking neuronal localisation. J Comp Neurol 421: 374-384

Moore DJ, Chambers JK, Murdock PR, Emson PC (2002) Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor. Neuropharmacology 43: 966-978

Moore DJ, Murdock PR, Watson JM, Faull RL, Waldvogel HJ, Szekeres PG, Wilson S, Freeman KB, Emson PC (2003) GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: possible role in neuroimmune function. Brain Res Mol Brain Res 118: 10-23

Moore H, Grace AA (2002) A role for electrotonic coupling in the striatum in the expression of dopamine receptor-mediated stereotypies. Neuropsychopharmacology 27: 980-992

Moosmann B, Behl C (2002) Antioxidants as treatment for neurodegenerative disorders. Expert Opin Investig Drugs 11: 1407-1435

Morales M, Backman C (2002) Coexistence of serotonin 3 (5-HT3) and CB1 cannabinoid receptors in interneurons of hippocampus and dentate gyrus. Hippocampus 12: 756-764

Morales M, Wang SD, Diaz-Ruiz O, Jho DH (2004) Cannabinoid CB1 receptor and serotonin 3 receptor subunit A (5-HT3A) are co-expressed in GABA neurons in the rat telencephalon. J Comp Neurol 468: 205-216

Moran AP, Rietschel ET, Kosunen TU, Zahringer U (1991) Chemical characterization of Campylobacter jejuni lipopolysaccharides containing N-acetylneuraminic acid and 2,3-diamino-2,3-dideoxy-D-glucose. J Bacteriol 173: 618-626

Moraru, II, Kaftan EJ, Ehrlich BE, Watras J (1999) Regulation of type 1 inositol 1,4,5-trisphosphate-gated calcium channels by InsP3 and calcium: Simulation of single channel kinetics based on ligand binding and electrophysiological analysis. J Gen Physiol 113: 837-849

Morefield SI, Keefer EW, Chapman KD, Gross GW (2000) Drug evaluations using neuronal networks cultured on microelectrode arrays. Biosens Bioelectron 15: 383-396

Morgans CW, Brandstatter JH, Kellerman J, Betz H, Wassle H (1996) A SNARE complex containing syntaxin 3 is present in ribbon synapses of the retina. J Neurosci 16: 6713-6721

Morishima N, Ikai A (1987) Active site organization of bacterial type I fatty acid synthetase. J Biochem (Tokyo) 102: 1451-1457

Morisset V, Ahluwalia J, Nagy I, Urban L (2001) Possible mechanisms of cannabinoid-induced antinociception in the spinal cord. Eur J Pharmacol 429: 93-100

Morisset V, Urban L (2001) Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. J Neurophysiol 86: 40-48

Morley KC, Li KM, Hunt GE, Mallet PE, McGregor IS (2004) Cannabinoids prevent the acute hyperthermia and partially protect against the 5-HT depleting effects of MDMA ("Ecstasy") in rats. Neuropharmacology 46: 954-965

Morozov YM, Freund TF (2003) Post-natal development of type 1 cannabinoid receptor immunoreactivity in the rat hippocampus. Eur J Neurosci 18: 1213-1222

Morris AP, Gallacher DV, Irvine RF, Petersen OH (1987) Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channels. Nature 330: 653-655

Morris SA, Nerou EP, Riley AM, Potter BV, Taylor CW (2002) Determinants of adenophostin A binding to inositol trisphosphate receptors. Biochem J 367: 113-120

Morton-Firth CJ, Shimizu TS, Bray D (1999) A free-energy-based stochastic simulation of the Tar receptor complex. J Mol Biol 286: 1059-1074

Morton LF, Peachey AR, Knight CG, Farndale RW, Barnes MJ (1997) The platelet reactivity of synthetic peptides based on the collagen III fragment alpha1(III)CB4. Evidence for an integrin alpha2beta1 recognition site involving residues 522-528 of the alpha1(III) collagen chain. J Biol Chem 272: 11044-11048

Mosedale DE, Grainger DJ (1999) An antibody present in normal human serum inhibits the binding of cytokines to their receptors in an in vitro system. Biochem J 343 Pt 1: 125-133

Motley A, Bright NA, Seaman MN, Robinson MS (2003) Clathrin-mediated endocytosis in AP-2-depleted cells. J Cell Biol 162: 909-918

Motobe T, Hashiguchi T, Uchimura T, Yamakuchi M, Taniguchi N, Komiya S, Maruyama I (2004) Endogenous cannabinoids are candidates for lipid mediators of bone cement implantation syndrome. Shock 21: 8-12

Movsesyan VA, Stoica BA, Cernak I, Dabaghyan EA, Faden AI (2002) Anandamide Induces Neuronal Apoptosis in Primary Neuronal Cultures. Society for Neuroscience Abstract Viewer and Itinerary Planner 2002

Msghina M, Millar AG, Charlton MP, Govind CK, Atwood HL (1999) Calcium entry related to active zones and differences in transmitter release at phasic and tonic synapses. J Neurosci 19: 8419-8434

Muhammad I, Li XC, Dunbar DC, ElSohly MA, Khan IA (2001) Antimalarial (+)-trans-hexahydrodibenzopyran derivatives from Machaerium multiflorum. J Nat Prod 64: 1322-1325

Mukhopadhyay S, Chapnick BM, Howlett AC (2002) Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. Am J Physiol Heart Circ Physiol 282: H2046-2054

Mukhopadhyay S, Cowsik SM, Lynn AM, Welsh WJ, Howlett AC (1999) Regulation of Gi by the CB1 cannabinoid receptor C-terminal juxtamembrane region: structural requirements determined by peptide analysis. Biochemistry 38: 3447-3455

Mukhopadhyay S, Das S, Howlett AC (2001) LPS-induced upregulation of CB2 cannabinoid receptors in RAW 264.7 macrophage cells is modulated by a cAMP-dependent protein kinase pathway. FASEB Journal 15

Mukhopadhyay S, Howlett AC (2001) CB1 receptor-G protein association. Subtype selectivity is determined by distinct intracellular domains. Eur J Biochem 268: 499-505

Mukhopadhyay S, McIntosh HH, Houston DB, Howlett AC (2000) The CB(1) cannabinoid receptor juxtamembrane C-terminal peptide confers activation to specific G proteins in brain. Mol Pharmacol 57: 162-170

Muller-Vahl KR (2003) Cannabinoids reduce symptoms of Tourette's syndrome. Expert Opin Pharmacother 4: 1717-1725

Muller BM, Kistner U, Kindler S, Chung WJ, Kuhlendahl S, Fenster SD, Lau LF, Veh RW, Huganir RL, Gundelfinger ED, Garner CC (1996) SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo. Neuron 17: 255-265

Muller BM, Kistner U, Veh RW, Cases-Langhoff C, Becker B, Gundelfinger ED, Garner CC (1995) Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein. J Neurosci 15: 2354-2366

Muller D, Sommer M, Kretzschmar M, Zimmermann T, Buko VU, Lukivskaya O, Dargel R (1991) Lipid peroxidation in thioacetamide-induced macronodular rat liver cirrhosis. Arch Toxicol 65: 199-203

Muller P, Chambaut-Guerin AM, Rossignol B (1985) Comparative effects of cytochalasin D on the protein discharge induced by alpha- and beta-adrenergic or cholinergic agonists in rat exorbital lacrimal glands. Biochim Biophys Acta 844: 158-166

Mulligan C, Rochford J, Denyer G, Stephens R, Yeo G, Freeman T, Siddle K, O'Rahilly S (2002) Microarray analysis of insulin and insulin-like growth factor-1 (IGF-1) receptor signaling reveals the selective up-regulation of the mitogen heparin-binding EGF-like growth factor by IGF-1. J Biol Chem 277: 42480-42487

Mundt C, Licence S, Shimizu T, Melchers F, Martensson IL (2001) Loss of precursor B cell expansion but not allelic exclusion in VpreB1/VpreB2 double-deficient mice. J Exp Med 193: 435-445

Mundy NI, Badcock NS, Hart T, Scribner K, Janssen K, Nadeau NJ (2004) Conserved genetic basis of a quantitative plumage trait involved in mate choice. Science 303: 1870-1873

Munnik T, Irvine RF, Musgrave A (1998) Phospholipid signalling in plants. Biochimica et Biophysica Acta 1389: 222-272

Munro S, Freeman M (2000) The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD. Curr Biol 10: 813-820

Munro S, Thomas KL, Abu-Shaar M (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365: 61-65

Murakami K, Yubisui T, Takeshita M, Miyata T (1989) The NH2-terminal structures of human and rat liver microsomal NADH-cytochrome b5 reductases. J Biochem (Tokyo) 105: 312-317

Murakami M, Masuda S, Kudo I (2003) Arachidonate release and prostaglandin production by group IVC phospholipase A2 (cytosolic phospholipase A2gamma). Biochem J 372: 695-702

Murakami S, Muramatsu M, Araki H, Otomo S (1994) Structure-activity relationships of unsaturated long chain fatty acids in relation to the inhibition of gastric H+,K(+)-ATPase. Res Commun Mol Pathol Pharmacol 85: 57-66

Murayama T, Ogawa Y (1994) Relationships among ryanodine receptor isoforms expressed in vertebrate skeletal muscles based on immunologic cross-reactivities. J Biochem (Tokyo) 116: 1117-1122

Murchie AI, Davis B, Isel C, Afshar M, Drysdale MJ, Bower J, Potter AJ, Starkey ID, Swarbrick TM, Mirza S, Prescott CD, Vaglio P, Aboul-ela F, Karn J (2004) Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA. J Mol Biol 336: 625-638

Murillo-Rodriguez E, Blanco-Centurion C, Sanchez C, Piomelli D, Shiromani PJ (2003) Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. Sleep 26: 943-947

Murillo-Rodriguez E, Cabeza R, Mendez-Diaz M, Navarro L, Prospero-Garcia O (2001) Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor. Neuroreport 12: 2131-2136

Murillo-Rodriguez E, Giordano M, Cabeza R, Henriksen SJ, Mendez Diaz M, Navarro L, Prospero-Garcia O (2001) Oleamide modulates memory in rats. Neurosci Lett 313: 61-64

Murillo-Rodriguez E, Sanchez-Alavez M, Navarro L, Martinez-Gonzalez D, Drucker-Colin R, Prospero-Garcia O (1998) Anandamide modulates sleep and memory in rats. Brain Res 812: 270-274

Murillo-Rodriguez E, Sanchez C, Piomelli D, Shiromani PJ (2003) The endocannabinoids, anandamide and 2 - arachidonyl glycerol modulating sleep via adenosine system. Society for Neuroscience Abstract Viewer and Itinerary Planner 2003

Murphy JW, Kendall DA (2003) Integrity of extracellular loop 1 of the human cannabinoid receptor 1 is critical for high-affinity binding of the ligand CP 55,940 but not SR 141716A. Biochem Pharmacol 65: 1623-1631

Murray J, Walmsley SR, Mecklenburgh KI, Cowburn AS, White JF, Rossi AG, Chilvers ER (2003) Hypoxic regulation of neutrophil apoptosis role: of reactive oxygen intermediates in constitutive and tumor necrosis factor alpha-induced cell death. Ann N Y Acad Sci 1010: 417-425

Mussinu JM, Ruiu S, Mule AC, Pau A, Carai MA, Loriga G, Murineddu G, Pinna GA (2003) Tricyclic pyrazoles. Part 1: synthesis and biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazol-based ligands for CB1and CB2 cannabinoid receptors. Bioorg Med Chem 11: 251-263

Musty RE, Reggio P, Consroe P (1995) A review of recent advances in cannabinoid research and the 1994 International Symposium on Cannabis and the Cannabinoids. Life Sci 56: 1933-1940

Muthian S, Nithipatikom K, Campbell WB, Hillard CJ (2000) Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. J Pharmacol Exp Ther 293: 289-295

Mutini C, Falzoni S, Ferrari D, Chiozzi P, Morelli A, Baricordi OR, Collo G, Ricciardi-Castagnoli P, Di Virgilio F (1999) Mouse dendritic cells express the P2X7 purinergic receptor: characterization and possible participation in antigen presentation. J Immunol 163: 1958-1965